AJ Journal of Medical Sciences

Volume: 1 Issue: 1

  • Open Access
  • Review Article

Multiomics: Concepts, Methods and Applications

A R Aroor1,∗

1Associate Research Professor, Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Center for Diabetes and Cardiovascular Research, Dalton Cardiovascular Research Center, School of Medicine, NR Investigator, University of Missouri, MO, Columbia, USA.
 

∗ Corresponding author. A R Aroor: [email protected]

 

Year: 2024, Page: 12-15, Doi: https://doi.org/10.71325/ajjms.v1i1.arora

Received: Dec. 20, 2024 Accepted: Dec. 23, 2024 Published: Dec. 30, 2024

Abstract

Multiomics is a high-throughput technology with multilayered system biology approach incorporating bioinformatic analysis of the data. At present it includes genomics, epigenomics, transcriptomics, proteomics, metabolomics, and gut microbiomics with advancement to the level of single cell analysis. Multiomics is an advancing approach (1) to understand the pathobiology of disease, (2) to identify sensitive biomarkers for the diagnosis of diseases as well as in monitoring and (3) to identify disease specific targets to treat the patient in the context of precision medicine as targeted therapeutics. In the present review, a brief account of various multiomic techniques is considered and relevant examples are pondered to reflect their applications in both preclinical and clinical translational research.

Keywords: Multiomics, Genomics, Proteomics, Metabolomics, Pathobiology

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Copyright

© 2024 Published by Laxmi Memorial Education Trust. This is an open-access article under CC BY 4.0 license. (https://creativecommons.org/licenses/by/4.0/)

Cite this article

A R Aroor. Multiomics: Concepts, Methods and Applications. AJ J Med Sci 2024;1(1):12–15

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